The results of the development of the composition and technology of production of soil ameliorant based on organic and mineral waste from beet crop rotation and sugar production are presented. The purpose of the study: to develop the composition of the soil ameliorant and the technology of complex utilization of beet sugar production waste and non-economic parts of beet crop rotation plants and to test the effectiveness on sugar beet crops. The problem of soil degradation due to the intensification of sugar beet production is solved by returning organic and mineral substances accumulated in sugar production waste and non-economic part of the biomass of beet crop rotation plants back to the soil for its reclamation. The ameliorant includes a defecate mixed with an aqueous solution of humates of low land peat and organic residues of biomass of beetroot crop rotation plants. Physical methods of activation of humates are used by exposure to ultrasonic vibrations and ultrahigh pressure of micro-explosions of air bubbles in a hydrodynamic cavitation generator, Accounting, observation and evaluation of biological and economic efficiency were carried out according to generally accepted methods and in accordance with the methodological recommendations of the All-Russian Scientific Research Institute of Plant Protection (VISR). Mathematical processing of crop data was carried out according to B.A. Dospekhov. It is shown that the introduction of ameliorant into the soil during the cultivation of sugar beet allowed to increase yields by 6.9%, and sugar harvesting by 11.2%. The main advantage of the proposed method of producing soil ameliorant is that it ensures the maximum possible return of nutrients carried out with the harvest back into the soil. In addition, the use of by-products and waste from the sugar industry makes it possible to return thousands of hectares of land occupied by landfills for use in agriculture.